| Most Yards Rushing (Game) |
342 | Chris Markey (St. Amant) | 2003 |
336 | Chris Markey (East. St. John) | 2003 |
303 | Chris Markey (Holy Cross) | 2003 |
| 288 | Willie Bradford (Chalmette) | 1985 |
| 275 | Eddie Torbio (LC Landry) | 1931 |
267 | Chris Markey (Warren Easton) | 2003 |
| 260 | Brandt Quick (Carver) | 1998 |
| 240 | Todd Golemi (Slidell) | 1993 |
236 | Chris Markey (Catholic High) | 2003 |
234 | Chris Markey (Kennedy) | 2003 |
231 | Chris Markey (Abramson) | 2003 |
| 219 | Gil Fenerty (DeLaSalle) | 1980 |
| 219 | Kenny Martin (St. Aloy.) | 1959 |
| 217 | Gerald Griffith (Redempt.) | 1948 |
| 212 | Pat Screen (St. Aloysius) | 1960 |
| 208 | Todd Golemi (Holy Cross) | 1993 |
| 207 | Pat Screen (Istrouma) | 1960 |
| 196 | John Petitbon (Pensacola) | 1947 |
| 190 | Brandt Quick (DeLaSalle) | 1998 |
| 187 | Brant Hocke (Destrehan) | 1997 |
| 187 | Will Washington (Reed) | 1998 |
